Amoxicillin Trihydrate (61336-70-7)
Kev piav qhia
● Amoxicillin Trihydrate (61336-70-7)
● CAS No.: 61336-70-7
● EINECS No.: 248-003-8
● MF: C16H19N3O5S
● Pob: 25kg / nruas
Khoom Paub meej
Amoxicillin trihydrate, semi-synthetic broad-spectrum penicillin, muaj tib yam tshuaj tua kab mob, cov nyhuv thiab siv raws li ampicillin.Amoxicillin trihydrate yog hydrate uas yog daim ntawv trihydrate ntawm amoxicillin;ib qho tshuaj tua kab mob semisynthetic, siv ib leeg lossis ua ke nrog cov poov tshuaj clavulanate (hauv qab lub npe lag luam Augmentin) rau kev kho mob ntawm ntau yam kab mob.Nws muaj lub luag haujlwm ua tshuaj tua kab mob thiab tshuaj tua kab mob.Nws muaj ib qho amoxicillin.Amoxicillin yog ib qho dav-spectrum, semisynthetic aminopenicillin tshuaj tua kab mob nrog cov kab mob bactericidal.Amoxicillin khi rau thiab inactivates penicillin-binding protein (PBP) 1A nyob rau sab hauv daim nyias nyias ntawm phab ntsa ntawm cov kab mob.Inactivation ntawm PBPs cuam tshuam nrog kev sib txuas ntawm peptidoglycan chains tsim nyog rau cov kab mob cell phab ntsa zog thiab rigidity.Qhov no cuam tshuam cov kab mob cell phab ntsa synthesis thiab ua rau cov kab mob ntawm cov phab ntsa tsis muaj zog thiab ua rau cov cell lysis.
Amoxicillin tau tshawb pom hauv xyoo 1958 thiab tuaj rau hauv kev siv tshuaj kho mob hauv xyoo 1972. Amoxil tau pom zoo rau kev siv tshuaj kho mob hauv Tebchaws Meskas hauv xyoo 1974, thiab hauv tebchaws United Kingdom hauv xyoo 1977. Nws yog nyob rau ntawm (WHO) Lub Koom Haum Saib Xyuas Kev Noj Qab Haus Huv Ntiaj Teb Cov Ntawv Teev Cov Tshuaj Tseem Ceeb. yog ib qho tshuaj tua kab mob ntau tshaj plaws hauv cov menyuam yaus.Amoxicillin muaj nyob rau hauv cov tshuaj generic.Nyob rau xyoo 2020, nws yog 40th feem ntau cov tshuaj kws kho mob hauv Tebchaws Meskas, nrog ntau dua 15 lab cov tshuaj.
Daim ntawv thov
Nws yog siv los kho cov kab mob, xws li mob hauv siab (xws li mob ntsws) thiab kho hniav abscesses.Nws kuj tuaj yeem siv ua ke nrog lwm cov tshuaj tua kab mob thiab tshuaj kho mob plab.Nws yog feem ntau sau rau cov menyuam yaus, kho pob ntseg thiab mob hauv siab.
| Cov ntsiab lus kuaj | Cov qauv | Cov txiaj ntsig |
| Assay | 95.0% ~ 102.0%. | 99.9% |
| PH | 3.5 ~ 5.5 hli | 4.6 |
| Qhov tshwm sim ntawm kev daws teeb meem | 0.5 mol / L HCL ≤ 2 # 2 mol/L NH4 OH 2# | 1#1# |
| Dej | 11.5% ~ 14.5% | 13.2% |
| Cov khoom muaj feem xyuam | impurity (max.) ≤1.0% | 0.13% |
| Kev sib hloov kho qhov muag tshwj xeeb | + 290 '' ~ + 315 '' | +305 ° |
| Sulfated tshauv | ≤ 1.0% | 0.1% |
| NN-Dimethylannline hmoov | ≤ 20ppm | Tsis txhob siv rau hauv kev tsim khoom |
| Methylen chloride | ≤600ppm | 296ppm ua |
| Triethylamine | ≤320ppm | 15 5ppm |
| Acetone | ≤3000ppm | 95ppm ua |
| Xaus: Ua raws li EP 6th Standard. | ||
