Ceftiofur Hydrochloride (103980-44-5)
Product Description
Ceftiofur yog ib qho tshuaj tua kab mob ntawm hom cephalosporin (tiam thib peb), muaj ntawv tso cai siv rau hauv cov tshuaj kho tsiaj.Nws yog thawj zaug piav nyob rau hauv 1987.
Nws tiv taus cov tshuaj tua kab mob enzyme beta-lactamase, thiab muaj kev ua haujlwm tawm tsam cov kab mob Gram-positive thiab Gram-negative.Cov kab mob E. coli resistant rau ceftiofur tau raug tshaj tawm.
Ceftiofur Hydrochloride yog hydrochloride ntsev daim ntawv ntawm ceftiofur, ib tug semisynthetic, beta-lactamase-ruaj khov, broad-spectrum, thib peb tiam cephalosporin nrog antibacterial kev ua.Ceftiofur khi rau thiab inactivates penicillin-binding proteins (PBPs) nyob rau hauv daim nyias nyias ntawm lub cell phab ntsa.PBPs yog cov enzymes koom nrog hauv cov theem kawg ntawm kev sib sau cov kab mob ntawm cov phab ntsa ntawm tes thiab hauv kev kho cov phab ntsa ntawm tes thaum loj hlob thiab faib.Inactivation ntawm PBPs cuam tshuam nrog kev sib txuas ntawm peptidoglycan chains tsim nyog rau cov kab mob cell phab ntsa zog thiab rigidity.Qhov no ua rau lub cev tsis muaj zog ntawm cov kab mob ntawm cov phab ntsa thiab ua rau cov cell lysis.
| Yam khoom | SPECIFICATIONS | TSEEM CEEB | |
| Qhov tshwm sim | Dawb rau Off-dawb Crystalline hmoov | Ua raws | |
| Kev txheeb xyuas | Lub sijhawm khaws cia ntawm lub hauv paus ncov hauv lub chromatogram tau nrog cov tshuaj ntsuam xyuas sib raug mus rau tus thawj xib fwb ncov nyob rau hauv lub chromatogram tau nrog kev siv tshuaj. | Ua raws | |
| Cov tshuaj chloride | Ua raws | ||
| Qhov tshwm sim ntawm kev daws teeb meem | Qhov tseeb | Tsis muaj zog tshaj No.1 Turbidity Standard | <1 |
| Xim | Tsis tsaus dua li txheej txheem tshuaj Y9 | <8 | |
| Solubility | Soluble hauv N, N- Dimethylacetamide, me ntsis Soluble nyob rau hauv 5% ntawm sodium bicarbonate thiab methanol. | Ua raws | |
| PH | 2.0 ~ 3.0 | 2.2 | |
| Cov ntsiab lus dej | 1.5% ~ 4.0% | 1.6% | |
| Kev hloov kho qhov muag tshwj xeeb | -115 ° ~ -127 ° | -117 ° | |
| Hnyav hlau | NMT 0.0020% | Ua raws | |
| Residue ntawm ignition | 0.20% NMT | 0.15% | |
| Cov khoom muaj feem xyuam | Qhov loj tshaj impurity | 0.20% NMT | 0.09 ib |
| Tag nrho impurities | 1.50% NMT | 0.38 ib | |
| Cov kuab tshuaj residue | Ethyl Acetate | NMT 0.5000% | 0 |
| THF | NMT 0.0720% | 0.006 ib | |
| Acetone | NMT 0.5000% | 0.2739% | |
| Benzene | NMT 0.0002% | 0.0001 | |
| Assay | Ceftiofur Hydrochloride | 98.0% NLT | 100.4% |
| Chloride | 6.0% ~ 6.5% | 6.2% | |
| Cov kab mob endotoxin | Tsawg dua 0.20EU / mg | Ua raws | |
| Tsis muaj menyuam | Conforms qhov kev xeem | Ua raws | |
| Particle loj | D (0,1) | <1 | 1.8 |
| D (0,5) | <4 | 1.4 | |
| D (0,9) | <7 | 3.7 | |
| D (1.0) | <10 | 4.2 | |
| TEEB MEEM | KEV TIV THAIV KOM TSEEM CEEB | ||
